SymBio PharmaceuticalsSymBio Pharmaceuticals Limited4582東証グロース医薬品FY ending Dec 2025, consolidated, J-GAAP

SymBio Pharmaceuticals revenue and profit

It lost about ¥340 for every ¥100 of sales at the operating level. Revenue changed -46.7% from the prior year.

Five-year trend

Revenue¥1.31B
FY ending Dec 2021: ¥8.26B¥8.26BFY ending Dec 2022: ¥10B¥10BFY ending Dec 2023: ¥5.59B¥5.59BFY ending Dec 2024: ¥2.45B¥2.45BFY ending Dec 2025: ¥1.31B¥1.31BFY21FY22FY23FY24FY25
Operating income-¥4.44B
FY ending Dec 2021: ¥1.02B¥1.02BFY ending Dec 2022: ¥1.96B¥1.96BFY ending Dec 2023: -¥811.7M-¥811.7MFY ending Dec 2024: -¥3.88B-¥3.88BFY ending Dec 2025: -¥4.44B-¥4.44BFY21FY22FY23FY24FY25
Operating margin-339.6%
FY ending Dec 2021: 12.3%12.3%FY ending Dec 2022: 19.6%19.6%FY ending Dec 2023: -14.5%-14.5%FY ending Dec 2024: -158.1%-158.1%FY ending Dec 2025: -339.6%-339.6%FY21FY22FY23FY24FY25

What drives ROE

Net margin × asset turnover = ROA; ROA × financial leverage = ROE

Net margin—
2021: 24.6%24.6%2022: 11.8%11.8%2122232425
Asset turnover—
2021: 0.98×0.98×2022: 0.96×0.96×2122232425
ROA-108.1%
2021: 24.0%24.0%2022: 11.3%11.3%2023: -21.1%-21.1%2024: -58.4%-58.4%2025: -108.1%-108.1%2122232425
Financial leverage—
2021: 1.36×1.36×2022: 1.29×1.29×2122232425
ROE—
2021: 32.6%32.6%2022: 14.6%14.6%2122232425
PeriodNet marginAsset turnoverROAFinancial leverageROE
202124.6%0.98×24.0%1.36×32.6%
202211.8%0.96×11.3%1.29×14.6%
2023——×-21.1%—×—
2024——×-58.4%—×—
2025——×-108.1%—×—

Financial leverage can raise ROE; a higher value alone does not describe a company's overall condition.

Asset intensity and goodwill

Annual trends in tangible-asset ratios and goodwill balance.

PPE ÷ revenue—
2022: 0.7%0.7%22232425
PPE ÷ total assets—
2022: 0.7%0.7%22232425

Ratios are derived from reported values. Goodwill is shown only when separately reported; it is not inferred from combined intangible assets. Definition

Investment and working-capital efficiency

Track R&D investment and how long operating capital remains tied up before sales turn into cash.

R&D spending¥3.3B
2022: ¥2.55B¥2.55B2023: ¥2.64B¥2.64B2024: ¥3.38B¥3.38B2025: ¥3.3B¥3.3B22232425
R&D / revenue252.2%
2022: 25.5%25.5%2023: 47.2%47.2%2024: 137.8%137.8%2025: 252.2%252.2%22232425

R&D is shown only for years with machine-readable disclosure. Days are estimates using year-end receivables, inventory and payables divided by annual revenue or cost of sales; financial companies are excluded.

Income statement (JPY millions)

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Revenue8,25710,0085,5902,4531,308
Cost of revenue2,4522,4081,179580360
Gross profit5,8047,6004,4111,873947
SG&A4,7845,6365,2235,7505,388
Operating income1,0161,964-812-3,877-4,441
Pretax income1,0012,106-1,195-3,807-4,749
Income tax-1,0319277672728
Net income attributable to owners2,0321,179-1,963-3,833-4,776
Operating margin12.3%19.6%-14.5%-158.1%-339.6%

Balance sheet (reported items)

Year-end figures from filings. Unreported items are omitted. Interest-bearing debt excludes lease liabilities.

Assets

Cash 75%
Other assets 25%

Funding

Other liabilities 67%
Equity 33%

Each bar totals 100% of assets; other is the residual.

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Cash and equivalents¥3.86B¥6.28B¥6.52B¥3.96B¥2.88B
Total assets¥8.45B¥10.4B¥8.17B¥4.97B¥3.87B
Net assets¥6.75B¥8.51B¥7.21B¥4.2B¥1.27B
Share capital¥17.2B¥17.5B¥18B¥18.3B¥19.2B
Property, plant and equipment¥83.6M¥69M———
Intangible assets excluding goodwill¥259.1M¥222.2M———
Current assets¥6.75B¥9.31B¥8.08B¥4.92B¥3.82B
Current liabilities¥1.52B¥1.92B¥956.6M¥766.2M¥1.29B
Total liabilities¥1.71B¥1.93B¥960.3M¥770.8M¥2.6B
Equity attributable to owners of parent¥6.23B¥8.09B¥6.94B¥3.87B¥911.2M
Retained earnings-¥28B-¥26.9B-¥28.9B-¥32.7B-¥37.5B
Treasury stock-¥86M-¥88.2M-¥89.1M-¥89.9M-¥89.9M

Sources

Show source documents (6)
  • EDINET (FSA Japan)

    有価証券報告書-第21期(2025/01/01-2025/12/31)

    ID S100XNE52026-03-24Open
  • EDINET (FSA Japan)

    有価証券報告書-第20期(2024/01/01-2024/12/31)

    ID S100VGDJ2025-03-25Open
  • EDINET (FSA Japan)

    有価証券報告書-第19期(2023/01/01-2023/12/31)

    ID S100T3FG2024-03-22Open
  • EDINET (FSA Japan)

    訂正有価証券報告書-第18期(2022/01/01-2022/12/31)

    ID S100QG6E2023-03-24Open
  • EDINET (FSA Japan)

    有価証券報告書-第17期(令和3年1月1日-令和3年12月31日)

    ID S100NPZC2022-03-29Open
  • EDINET (FSA Japan)

    有価証券報告書-第16期(令和2年1月1日-令和2年12月31日)

    ID S100L0KX2021-03-24Open

Extracted from XBRL: 40

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