Cyfuse BiomedicalCyfuse Biomedical K.K.4892東証グロース医薬品FY ending Dec 2025, non-consolidated, J-GAAP

Cyfuse Biomedical revenue and profit

It lost about ¥359 for every ¥100 of sales at the operating level. Revenue changed +324.3% from the prior year.

Five-year trend

Revenue¥231M
FY ending Dec 2021: ¥708.2M¥708.2MFY ending Dec 2022: ¥374.5M¥374.5MFY ending Dec 2023: ¥61.1M¥61.1MFY ending Dec 2024: ¥54.4M¥54.4MFY ending Dec 2025: ¥231M¥231MFY21FY22FY23FY24FY25
Operating income-¥828.2M
FY ending Dec 2021: ¥70.6M¥70.6MFY ending Dec 2022: -¥425.1M-¥425.1MFY ending Dec 2023: -¥697.4M-¥697.4MFY ending Dec 2024: -¥896.1M-¥896.1MFY ending Dec 2025: -¥828.2M-¥828.2MFY21FY22FY23FY24FY25
Operating margin-358.5%
FY ending Dec 2021: 10.0%10.0%FY ending Dec 2022: -113.5%-113.5%FY ending Dec 2023: -1141.2%-1141.2%FY ending Dec 2024: -1645.9%-1645.9%FY ending Dec 2025: -358.5%-358.5%FY21FY22FY23FY24FY25

What drives ROE

Net margin × asset turnover = ROA; ROA × financial leverage = ROE

Net margin—
2021: 20.2%20.2%2122232425
Asset turnover—
2021: 0.27×0.27×2122232425
ROA-19.6%
2021: 5.4%5.4%2022: -12.7%-12.7%2023: -13.0%-13.0%2024: -22.6%-22.6%2025: -19.6%-19.6%2122232425
Financial leverage—
2021: 1.39×1.39×2122232425
ROE—
2021: 7.5%7.5%2122232425
PeriodNet marginAsset turnoverROAFinancial leverageROE
202120.2%0.27×5.4%1.39×7.5%
2022——×-12.7%—×—
2023——×-13.0%—×—
2024——×-22.6%—×—
2025——×-19.6%—×—

Financial leverage can raise ROE; a higher value alone does not describe a company's overall condition.

Asset intensity and goodwill

Annual trends in tangible-asset ratios and goodwill balance.

PPE ÷ revenue67.1%
2021: 3.9%3.9%2022: 50.5%50.5%2023: 278.1%278.1%2024: 260.5%260.5%2025: 67.1%67.1%2122232425
PPE ÷ total assets3.6%
2021: 1.0%1.0%2022: 3.9%3.9%2023: 4.0%4.0%2024: 4.0%4.0%2025: 3.6%3.6%2122232425

Ratios are derived from reported values. Goodwill is shown only when separately reported; it is not inferred from combined intangible assets. Definition

Investment and working-capital efficiency

Track R&D investment and how long operating capital remains tied up before sales turn into cash.

R&D spending¥416.5M
2022: ¥303.7M¥303.7M2023: ¥375.6M¥375.6M2024: ¥469.6M¥469.6M2025: ¥416.5M¥416.5M2122232425
R&D / revenue180.3%
2022: 81.1%81.1%2023: 614.6%614.6%2024: 862.4%862.4%2025: 180.3%180.3%2122232425

R&D is shown only for years with machine-readable disclosure. Days are estimates using year-end receivables, inventory and payables divided by annual revenue or cost of sales; financial companies are excluded.

Income statement (JPY millions)

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Revenue7083746154231
Cost of revenue1381332338117
Gross profit5712413817114
SG&A500667735913942
Operating income71-425-697-896-828
Pretax income145-472-586-870-761
Income tax22323
Net income attributable to owners143-474-589-872-764
Operating margin10.0%-113.5%-1141.2%-1645.9%-358.5%

Balance sheet (reported items)

Year-end figures from filings. Unreported items are omitted. Interest-bearing debt excludes lease liabilities.

Assets

Cash 56%
4%
0%
Other assets 40%

Funding

Other liabilities 35%
Equity 65%

Each bar totals 100% of assets; other is the residual.

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Cash and equivalents¥1.61B¥3.44B¥2.87B¥2.05B¥2.38B
Total assets¥2.65B¥4.82B¥4.21B¥3.52B¥4.27B
Net assets¥1.9B¥3.77B¥3.2B¥2.54B¥2.76B
Share capital¥100M¥1.27B¥1.28B¥1.36B¥1.83B
Property, plant and equipment¥27.3M¥189M¥170M¥141.8M¥155.1M
Intangible assets excluding goodwill¥4.8M¥5.5M¥4.4M¥4.2M¥3.4M
Current assets¥2.56B¥4.57B¥3.99B¥3.24B¥3.93B
Current liabilities¥386.3M¥682.5M¥666.3M¥648.6M¥866.1M
Short-term borrowings¥128.8M¥467.3M¥550M¥507.8M¥485M
Long-term borrowings¥359.8M¥363M¥345M¥327M¥642.3M
Total liabilities¥746.1M¥1.05B¥1.01B¥975.6M¥1.51B
Equity attributable to owners of parent¥1.9B¥3.77B¥3.2B¥2.49B¥2.66B
Retained earnings-¥922.9M-¥1.4B-¥1.99B-¥2.86B-¥3.62B

Sources

Show source documents (4)
  • EDINET (FSA Japan)

    有価証券報告書-第16期(2025/01/01-2025/12/31)

    ID S100XV4M2026-03-27Open
  • EDINET (FSA Japan)

    有価証券報告書-第15期(2024/01/01-2024/12/31)

    ID S100VGO72025-03-26Open
  • EDINET (FSA Japan)

    有価証券報告書-第14期(2023/01/01-2023/12/31)

    ID S100T55F2024-03-27Open
  • EDINET (FSA Japan)

    有価証券報告書-第13期(2022/01/01-2022/12/31)

    ID S100QGWF2023-03-28Open

Extracted from XBRL: 39 / Derived from other figures: 1

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