Industry map/Healthcare & Consumer Goods

Biotech & Regenerative Medicine industry map

Who earns the money in Biotech & Regenerative Medicine, and who keeps it. When a company spans several industries, only the relevant segment is counted.

FY2025 · 24 companies · ¥61.3B

Industry map

Companies ordered by revenue, connected by ownership (major shareholders). Arrows point from the shareholder to the investee.

Industry size (revenue)
¥61.3B

YoY -6.6%

Companies
24
Avg. salary(parent only)
¥6.5M

Avg. age 44.0

Industry weather
Rainy

Takara Holdings[2531]

Takara Bio Group

#1
Revenue
¥40.3B▼10.5%
Operating income
-¥4.69BTurned to loss

Margin -11.6%

Whole company: Revenue ¥394.3B · Net income ¥11.7B

Avg. salary ¥7.6M · 49.8(parent only)

Kidswell Bio[4584]

#2▲
Revenue
¥6.59B▲29.7%
Operating income
-¥138.5MTurned to loss

Margin -2.1%

Avg. salary ¥9.2M · 48.6(parent only)

  • Nano Holdings owns 2.0%

StemCell Institute[7096]

#3▲
Revenue
¥2.81B▲4.9%
Operating income
¥202.7M▼51.6%

Margin 7.2%

Avg. salary ¥5.1M · 37.1(parent only)

Kohjin Bio[177A]

Tissue culture business

#4▲
Revenue
¥2.54B▲11.9%
Operating income
¥946.5M▲23.7%

Margin 37.3%

Whole company: Revenue ¥4.94B · Net income ¥251M

Avg. salary ¥5.5M · 38.6(parent only)

ReproCELL[4978]

Research Support Business + 1 more

#5▼
Revenue
¥2.23B▼25.0%
Operating income
¥52.6M▼93.3%

Margin 2.4%

Whole company: Revenue ¥2.23B · Net income -¥591.7M

Avg. salary ¥6.1M · 34.2(parent only)

Japan Tissue Engineering[7774]

Regenerative Medicine Business + 2 more

#6
Revenue
¥2.18B▼11.1%
Operating income
¥458.5M▼34.3%

Margin 21.0%

Whole company: Revenue ¥2.18B · Net income -¥734.8M

Avg. salary ¥6.1M · 39.7(parent only)

Waqoo[4937]

Medical support

#7▲
Revenue
¥999M▲59.3%
Operating income
¥216.1M▲237.7%

Margin 21.6%

Whole company: Revenue ¥1.96B · Net income ¥44.1M

Avg. salary ¥5.9M · 38.6(parent only)

PRISM BioLab[206A]

#8▲
Revenue
¥677.3M▲121.6%
Operating income
-¥774.5M

Margin -114.3%

Avg. salary ¥9.5M · 45.0(parent only)

DyDo GROUP HOLDINGS[2590]

DyDo Pharma

#9▲
Revenue
¥606M▲7475.0%
Operating income
-¥321M

Margin -53.0%

Whole company: Revenue ¥241.2B · Net income -¥30.3B

Avg. salary ¥8.5M · 40.8(parent only)

D.Western Therapeutics Institute[4576]

#10▲
Revenue
¥387.6M▼17.8%
Operating income
-¥619.9M

Margin -159.9%

Avg. salary ¥6.7M · 50.8(parent only)

Pharma Foods International[2929]

Bio Medical

#11▲
Revenue
¥331M▼30.8%
Operating income
-¥378M

Margin -114.2%

Whole company: Revenue ¥65.3B · Net income ¥368M

Avg. salary ¥5.5M · 39.3(parent only)

Stella Pharma[4888]

#12▼
Revenue
¥323.4M▼66.4%
Operating income
-¥749M

Margin -231.6%

Avg. salary ¥6.6M · 48.5(parent only)

※ Card revenue and operating income cover only the segment in this industry; “Whole company” shows consolidated revenue and net income.

Other companies: Cyfuse Biomedical · Cuorips · Tsubota Laboratory · Nano Holdings · Perseus Proteomics · Medrx · Shin Nippon Biomedical Laboratories · Kringle Pharma · Oncolys BioPharma · J-Holdings · CellSeed · Medinet

The weather is derived mechanically from year-over-year totals of revenue and operating income (both up = sunny, both down = rainy).

Switch years to see how the map shifts

Who earns the money

Area = revenue from businesses in this industry. Color = operating margin.

LossHigh margin(middle = 0% margin)

Who makes a profit

Across = revenue (log scale), up = operating margin, bubble size = operating income.

Ranking and momentum

RankCompany (business)RevenueShareOp. marginCAGRFCF*
1Takara HoldingsTakara Bio Group¥40.3B65.8%-11.6%-12.2%-¥4.85B
2▲1Kidswell Bio¥6.59B10.8%-2.1%+43.1%-¥1.11B
3▲2StemCell Institute¥2.81B4.6%7.2%—-¥453.3M
4▲3Kohjin BioTissue culture business¥2.54B4.1%37.3%+15.5%-¥271.6M
5▼1ReproCELLResearch Support Business + 1 more¥2.23B3.6%2.4%-0.0%-¥481.7M
6Japan Tissue EngineeringRegenerative Medicine Business + 2 more¥2.18B3.6%21.0%+3.9%-¥565.7M
7▲4WaqooMedical support¥999M1.6%21.6%—-¥56.8M
8▲6PRISM BioLab¥677.3M1.1%-114.3%+144.9%-¥1.54B
9▲15DyDo GROUP HOLDINGSDyDo Pharma¥606M1.0%-53.0%—-¥1.28B
10▲3D.Western Therapeutics Institute¥387.6M0.6%-159.9%-1.7%-¥496.5M
11▲1Pharma Foods InternationalBio Medical¥331M0.5%-114.2%-3.1%-¥2B
12▼3Stella Pharma¥323.4M0.5%-231.6%+34.1%-¥346.2M
13▲8Cyfuse Biomedical¥231M0.4%-358.5%-24.4%-¥582.4M
14▲3Cuorips¥212.3M0.3%-509.2%—-¥1.11B
15▼7Tsubota Laboratory¥200M0.3%-393.9%-25.3%-¥586.6M
16▲3Nano Holdings¥174.5M0.3%-553.6%——
17▲1Perseus Proteomics¥135.5M0.2%-549.8%+17.2%-¥663.3M
18▼3Medrx¥128.1M0.2%-735.4%+97.9%-¥970.9M
19▲3Shin Nippon Biomedical LaboratoriesTranslational Research¥105.5M0.2%-3818.2%+72.0%¥2.99B
20Kringle Pharma¥72.2M0.1%-1259.4%-29.3%—
21▲2Oncolys BioPharma¥28.5M0.0%-7090.6%-54.1%-¥1.94B
22newJ-HoldingsRegenerative medicine-related business¥6M0.0%-1084.2%—-¥529.4M
23▲2CellSeedCell-Sheet regenerative medicine¥1.9M0.0%-38558.9%—-¥1.02B
24▲3MedinetCellular and tissue-based product business¥219K0.0%-186290.4%+1.5%-¥1.45B

* FCF is company-wide (not disclosed by segment). CAGR covers the available years, up to five.

How they make money differently

Where each company's ¥100 of sales goes, and how much it keeps (company-wide).

  • Cost of sales
  • SG&A
  • Operating profit

Ownership links

From the major-shareholder section of annual securities reports.

The company on each card is a major shareholder of the companies listed under it (latest 'major shareholders' disclosure). 50%+ is labelled subsidiary and 20%+ affiliate, based on ownership alone. Stakes under 3% are omitted.

Compare the leaders side by side

All companies in Biotech & Regenerative Medicine (by revenue)

All 30 companies in this industry, ranked by revenue in each company's latest fiscal year. For companies that belong through one business segment, the figure is that segment's revenue.

  1. Takara Holdings¥40.3B · -11.6%
  2. PeptiDream¥31.3B · 66.9%
  3. Nxera Pharma¥12.8B
  4. Kidswell Bio¥6.59B · -2.1%
  5. StemCell Institute¥2.81B · 7.2%
  6. Kohjin Bio¥2.54B · 37.3%
  7. ReproCELL¥2.23B · 2.4%
  8. Japan Tissue Engineering¥2.18B · 21.0%
  9. Waqoo¥999M · 21.6%
  10. Heartseed¥873.6M · -118.9%
  11. PRISM BioLab¥677.3M · -114.3%
  12. Solasia Pharma¥617M
  13. DyDo GROUP HOLDINGS¥606M · -53.0%
  14. D.Western Therapeutics Institute¥387.6M · -159.9%
  15. Pharma Foods International¥331M · -114.2%
  16. Stella Pharma¥323.4M · -231.6%
  17. Cyfuse Biomedical¥231M · -358.5%
  18. Cuorips¥212.3M · -509.2%
  19. Tsubota Laboratory¥200M · -393.9%
  20. Nano Holdings¥174.5M · -553.6%
  21. Perseus Proteomics¥135.5M · -549.8%
  22. Medrx¥128.1M · -735.4%
  23. Healios¥121M
  24. Shin Nippon Biomedical Laboratories¥105.5M · -3818.2%
  25. Kringle Pharma¥72.2M · -1259.4%
  26. Oncolys BioPharma¥28.5M · -7090.6%
  27. J-Holdings¥6M · -1084.2%
  28. CellSeed¥1.9M · -38558.9%
  29. BrightPath Biotherapeutics¥1.1M · -102464.1%
  30. Medinet¥219K · -186290.4%

Revenue · Op. margin

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