D.Western Therapeutics InstituteD.Western Therapeutics Institute, Inc.4576東証グロース医薬品FY ending Dec 2025, consolidated, J-GAAP

D.Western Therapeutics Institute revenue and profit

It lost about ¥160 for every ¥100 of sales at the operating level. Revenue changed -17.8% from the prior year.

Five-year trend

Revenue¥387.6M
FY ending Dec 2021: ¥414.4M¥414.4MFY ending Dec 2022: ¥448.1M¥448.1MFY ending Dec 2023: ¥428.4M¥428.4MFY ending Dec 2024: ¥471.6M¥471.6MFY ending Dec 2025: ¥387.6M¥387.6MFY21FY22FY23FY24FY25
Operating income-¥619.9M
FY ending Dec 2021: -¥171.6M-¥171.6MFY ending Dec 2022: -¥305.9M-¥305.9MFY ending Dec 2023: -¥798.6M-¥798.6MFY ending Dec 2024: -¥1.21B-¥1.21BFY ending Dec 2025: -¥619.9M-¥619.9MFY21FY22FY23FY24FY25
Operating margin-159.9%
FY ending Dec 2021: -41.4%-41.4%FY ending Dec 2022: -68.3%-68.3%FY ending Dec 2023: -186.4%-186.4%FY ending Dec 2024: -256.5%-256.5%FY ending Dec 2025: -159.9%-159.9%FY21FY22FY23FY24FY25

What drives ROE

Net margin × asset turnover = ROA; ROA × financial leverage = ROE

ROA-32.9%
2021: -6.0%-6.0%2022: -15.9%-15.9%2023: -30.5%-30.5%2024: -63.8%-63.8%2025: -32.9%-32.9%2122232425
PeriodNet marginAsset turnoverROAFinancial leverageROE
2021——×-6.0%—×—
2022——×-15.9%—×—
2023——×-30.5%—×—
2024——×-63.8%—×—
2025——×-32.9%—×—

Financial leverage can raise ROE; a higher value alone does not describe a company's overall condition.

Asset intensity and goodwill

Annual trends in tangible-asset ratios and goodwill balance.

PPE ÷ revenue2.4%
2020: 1.5%1.5%2021: 1.1%1.1%2022: 2.3%2.3%2023: 2.3%2.3%2024: 2.4%2.4%2025: 2.4%2.4%202122232425
PPE ÷ total assets0.4%
2020: 0.2%0.2%2021: 0.2%0.2%2022: 0.3%0.3%2023: 0.4%0.4%2024: 0.7%0.7%2025: 0.4%0.4%202122232425

Ratios are derived from reported values. Goodwill is shown only when separately reported; it is not inferred from combined intangible assets. Definition

Investment and working-capital efficiency

Track R&D investment and how long operating capital remains tied up before sales turn into cash.

R&D spending¥669M
2020: ¥350M¥350M2021: ¥316M¥316M2022: ¥469M¥469M2023: ¥930M¥930M2024: ¥1.37B¥1.37B2025: ¥669M¥669M202122232425
R&D / revenue172.6%
2020: 98.4%98.4%2021: 76.3%76.3%2022: 104.7%104.7%2023: 217.1%217.1%2024: 289.9%289.9%2025: 172.6%172.6%202122232425

R&D is shown only for years with machine-readable disclosure. Days are estimates using year-end receivables, inventory and payables divided by annual revenue or cost of sales; financial companies are excluded.

Income statement (JPY millions)

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Revenue414448428472388
Cost of revenue2028374739
Gross profit394421392425349
SG&A5667261,1901,634969
Operating income-172-306-799-1,210-620
Pretax income-160-440-827-1,289-630
Income tax22222
Net income attributable to owners-149-430-812-1,290-632
Operating margin-41.4%-68.3%-186.4%-256.5%-159.9%

Balance sheet (reported items)

Year-end figures from filings. Unreported items are omitted. Interest-bearing debt excludes lease liabilities.

Assets

Cash 79%
0%
0%
7%
Other assets 14%

Funding

Other liabilities 34%
Equity 66%

Each bar totals 100% of assets; other is the residual.

ItemFY ending Dec 2021FY ending Dec 2022FY ending Dec 2023FY ending Dec 2024FY ending Dec 2025
Cash and equivalents¥1.93B¥2.33B¥1.87B¥1.13B¥1.71B
Total assets¥2.46B¥2.96B¥2.37B¥1.67B¥2.17B
Net assets¥2.04B¥1.87B¥1.28B¥733.9M¥1.44B
Share capital¥573.2M¥714.2M¥831.6M¥1.2B¥697.3M
Property, plant and equipment¥4.6M¥10.1M¥10M¥11.2M¥9.2M
Intangible assets excluding goodwill¥166.6M¥124.5M¥86.5M¥44.4M¥2.4M
Investment securities¥122.5M¥153.6M¥141.5M¥142.8M¥142.7M
Current assets¥2.16B¥2.66B¥2.14B¥1.48B¥2.02B
Current liabilities¥193.2M¥211.2M¥194M¥132.6M¥203.9M
Long-term borrowings¥210.5M¥113M¥269.5M¥476.4M¥506.1M
Bonds———¥302.5M—
Total liabilities¥427.7M¥1.08B¥1.09B¥935.6M¥734M
Non-controlling interests¥28.2M¥16M———
Equity attributable to owners of parent¥2B¥1.86B¥1.28B¥732.1M¥1.43B
Retained earnings-¥1.2B-¥1.63B-¥2.44B-¥3.73B-¥543.6M
Treasury stock——¥0¥0¥0

Sources

Show source documents (6)
  • EDINET (FSA Japan)

    有価証券報告書-第28期(2025/01/01-2025/12/31)

    ID S100XS4G2026-03-23Open
  • EDINET (FSA Japan)

    有価証券報告書-第27期(2024/01/01-2024/12/31)

    ID S100VFSO2025-03-25Open
  • EDINET (FSA Japan)

    有価証券報告書-第26期(2023/01/01-2023/12/31)

    ID S100T4H92024-03-27Open
  • EDINET (FSA Japan)

    有価証券報告書-第25期(2022/01/01-2022/12/31)

    ID S100QHG22023-03-30Open
  • EDINET (FSA Japan)

    有価証券報告書-第24期(令和3年1月1日-令和3年12月31日)

    ID S100NR772022-03-29Open
  • EDINET (FSA Japan)

    有価証券報告書-第23期(令和2年1月1日-令和2年12月31日)

    ID S100KZGC2021-03-23Open

Extracted from XBRL: 42 / Derived from other figures: 1

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